Vaccines and Hypervariable Viruses

Name: Vaccines and Hypervariable Viruses
Brand: VDM Verlag
SKU: 9783639049626
Price: 284.24 PLN
Availability: InStock

Design and Development of HIV-1, HCV, and SARS-CoV Candidate Vaccines

Autor: Ali Azizi

Język:

Oprawa: Miękka

Wydawca: VDM Verlag

Dostępność: Na zamówienie

Wysyłamy za 17-27 dni

284.24 zł

It is difficult to induce protective immunity against most RNA viruses. However, there is strong evi...

Informacje o książce

Autor

Ali Azizi

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2009

strony

196

EAN

9783639049626

ISBN

3639049624

Enbook ID

06814482

Wydawca

VDM Verlag

Waga

295

Wymiary

152 x 229 x 11

Pełny opis

It is difficult to induce protective immunity against most RNA viruses. However, there is strong evidence that humoral and especially cellular immune responses play crucial roles in the control of established RNA viral infections. Herein, correlates of protective immunity against HIV-1, HCV and SARS- CoV were assessed by various strategies. In the first study, we showed that a combination of monocistronic DNA constructs expressing HIV-1 structural genes, HIV-1 recombinant proteins and a potent adjuvant is able to induce humoral and cellular immune responses in HLA.A2.1 mice. In the second HIV-1 study, a synergistic effect between HIV- 1 and hepatitis C (HCV) immunogens was detected that may lead to induction of multi-specific immune responses against both HIV and HCV. In the third study, a high level of specific SARS-CD8+T-cell response was demonstrated in mice that received DNA vaccine expressing the SARS-nucleocapsid, protein and XIAP (X-link inhibitor of apoptosis) as an adjuvant.

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Vaccines and Hypervariable Viruses

Design and Development of HIV-1, HCV, and SARS-CoV Candidate Vaccines

Informacje o książce

Pełny opis

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