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Książka Targeted Protein Degradation Christopher Hickey

Targeted Protein Degradation

Autor: Christopher Hickey, Miklos Bekes
Język: Angielski
Oprawa: Twarda
Wydawca: Springer US
Dostępność: Dostępna u dostawcy
Wysyłamy za 10-18 dni
842.10 zł
This volume contains a collection of innovative techniques for studying targeted protein degradation...

Informacje o książce

Autor
Christopher Hickey, Miklos Bekes
Język
Angielski
Oprawa
Książka - Twarda
Data wydania
2021
strony
364
EAN
9781071616642
ISBN
1071616641
Enbook ID
35540254
Wydawca
Springer US
Waga
881
Wymiary
183 x 260 x 25

Pełny opis

This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

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