Structural Alignment

Name: Structural Alignment
Brand: VDM Verlag
SKU: 9783639279368
Price: 205.41 PLN
Availability: InStock

A Graph-Theoretic Approach

Autor: Layal Kazma

Język:

Oprawa: Miękka

Wydawca: VDM Verlag

Dostępność: Na zamówienie

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205.41 zł

Structural alignment is the process of finding similarities between a pair of proteins based on thei...

Informacje o książce

Autor

Layal Kazma

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2011

strony

EAN

9783639279368

ISBN

3639279360

Enbook ID

06835132

Wydawca

VDM Verlag

Waga

127

Wymiary

152 x 229 x 5

Pełny opis

Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection of such similarities could reveal evolutionary relationships and predict the functions of different proteins. Despite the existing algorithms, the protein structure alignment problem is not completely solved. In this work a graph-theoretic approach is considered, which consists of representing tertiary protein structures as labeled graphs, and interpreting the structural alignment problem as a particular case of the Maximum Common Subgraph (MCS) problem. Our algorithm was then implemented under parallel platforms using a combination of threads and message passing techniques. Experiments were performed on a set of proteins selected randomly from the Protein Data Bank. The experiments proved the time- efficiency and accuracy of our method when compared to several other algorithms.

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Structural Alignment

A Graph-Theoretic Approach

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