Smart Hydrogels for Controlled Drug Release

Name: Smart Hydrogels for Controlled Drug Release
Brand: LAP Lambert Academic Publishing
SKU: 9783846544983
Price: 295.59 PLN
Availability: InStock

Chitosan-Based Smart Hydrogels

Autor: Ibrahim M. El-Sherbiny

Język:

Oprawa: Miękka

Wydawca: LAP Lambert Academic Publishing

Dostępność: Dostępna u dostawcy

Wysyłamy za 8-11 dni

295.59 zł

Controlled drug release enhances the safety, efficacy and reliability of drug therapy. The number of...

Informacje o książce

Autor

Ibrahim M. El-Sherbiny

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2011

strony

208

EAN

9783846544983

Enbook ID

06929277

Wydawca

LAP Lambert Academic Publishing

Waga

328

Wymiary

150 x 220 x 12

Pełny opis

Controlled drug release enhances the safety, efficacy and reliability of drug therapy. The number of polymers suitable for the controlled release of viable therapeutics is quite limited due to inherent toxicity or lack of certain properties such as biodegradability. Chitosan, a non-toxic and biodegradable polymer was utilized as an ideal base polymer for the development of a series of new smart hydrogels for the use in the site-specific delivery of drugs to the gastrointestinal tract. The chitosan-based smart hydrogels were obtained particularly via three main approaches. The first approach was the incorporation of chitosan into interpenetrating networks with either a hydrophilic polymer or with hydrophilic monomers treated to bring about in situ copolymerization in presence of a crosslinking agent. The second approach was the grafting of suitable hydrophilic vinyl monomers onto chitosan followed by crosslinking. In the third strategy, chitosan was modified in such a fashion that the resulting smart hydrogels could be tailored for utilization in intestine targeted delivery of peptide and protein drugs with a potential protection of the drugs from the harsh acidity of the stomach.

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Smart Hydrogels for Controlled Drug Release

Chitosan-Based Smart Hydrogels

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