Seeking Cures

Design of Therapies for Genetically Determined Diseases

Autor: Moyra Smith

Język:

Oprawa: Twarda

Wydawca: Oxford University Press Inc

Dostępność: Dostępna u dostawcy

Wysyłamy za 10-18 dni

376.61 zł

Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose d...

Informacje o książce

Autor

Moyra Smith

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

2013

strony

320

EAN

9780199915866

ISBN

0199915865

Enbook ID

04536631

Wydawca

Oxford University Press Inc

Waga

588

Wymiary

155 x 244 x 20

Pełny opis

Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose diseases that are caused by gene mutations, changes in genome structures, and altered gene expression; increased emphasis is now placed on translational research the clinical treatment of these genetically determined diseases. Seeking Cures outlines the progress and implications of science's quest to identify therapeutic targets and initiate novel treatments at the gene, RNA, protein, and physiological levels. Also considered are aspects of treatment at the cellular level (e.g., those with hematopoietic stem cells or induced pluripotent stem cells). Topics covered in this text include: * outline of the processes typical for identifying disease-modifying therapies * examples of newer therapeutic approaches in use or under investigation to treat lysosomal storage diseases, inborn errors of metabolism, mitochondrial functional defects, and specific monogenic diseases * therapeutic designs for specific complex common diseases, including Alzheimer's disease, cancer, and autism Through these specific examples, Seeking Cures provides a glimpse at the pursuit-and future-of personalized medicine.

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Seeking Cures

Design of Therapies for Genetically Determined Diseases

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