Książka Peptidomimetics Protocols Wieslaw M. Kazmierski

Peptidomimetics Protocols

Język: Angielski
Oprawa: Twarda
Dostępność: Dostępna u dostawcy
Wysyłamy za 10-13 dni
429.51
A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds,...

Informacje o książce

Język
Angielski
Oprawa
Książka - Twarda
Data wydania
1998
strony
549
EAN
9780896035171
ISBN
0896035174
Enbook ID
01400753
Waga
2260
Wymiary
155 x 235 x 36

Pełny opis

A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds, turn mimetics, peptide-bound replacements, and enzyme inhibitors. Topics range from unusual syntheses of amino acids to the use of a variety of linear and heterocyclic scaffolds in place of the peptide backbone. Important chemical procedures and methods include the transient protection of charged peptides as neutral prodrugs for improved blood-brain penetration and the replacement of peptide bonds with heterocyclic rings, olefins and fluoroolefins, and ketomethylenes. Synthetic protocols towards the transition-state mimics and reactive "warheads," applicable in enzyme inhibitors, are also disclosed.

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