Pediatric Hematology

Name: Pediatric Hematology
Brand: Humana Press Inc.
SKU: 9781588290434
Price: 476.36 PLN
Availability: InStock

Methods and Protocols

Autor: Nicholas J. Goulden, Colin G. Steward

Język:

Oprawa: Twarda

Wydawca: Humana Press Inc.

Dostępność: Dostępna u dostawcy w małych ilościach

Wysyłamy za 13-18 dni

476.36 zł

Molecular techniques are now an integral part of the practice of modern pediatric hematology. In Ped...

Informacje o książce

Autor

Nicholas J. Goulden, Colin G. Steward

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

2003

strony

272

EAN

9781588290434

ISBN

1588290433

Enbook ID

01430203

Wydawca

Humana Press Inc.

Waga

1280

Wymiary

155 x 235 x 24

Pełny opis

Molecular techniques are now an integral part of the practice of modern pediatric hematology. In Pediatric Hematology: Methods and Protocols, hands-on masters of laboratory techniques describe their best methods for investigating and detecting a wide variety of hematological disorders. Here, the reader will find cutting-edge molecular protocols for the diagnosis of Fanconi anemia, dyskeratosis congenita, immunodeficiency, and most forms of hemoglobinopathy. In addition, there are detailed methods for molecular human platelet antigen genotyping, an effective PCR procedure for thrombophilia screening, and protocols for fluorescent in situ hybridization for cases in which insufficient metaphases are recovered or cryptic translocations are not visible. Since the measurement of minimal residual disease (MRD) provides a much more accurate risk-directed therapy, three methods are presented for detecting residual leukemia below the threshold of light microscopy, along with relatively simple, rapid, and inexpensive methods for the detection of MRD in ALL and AML. On the cutting-edge of technology, microarrays are used for the analysis of gene expression in childhood leukemia, and novel methods of graft engineering and reduced intensity conditioning regimens are applied to tissue typing for the assessment of donor/recipient chimerism. Each readily reproducible protocol is described in step-by-step detail and includes an introduction to the principle behind the method, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls.§Cutting-edge and highly practical, Pediatric Hematology: Methods and Protocols offers experimental and clinical investigators a gold-standard collection of reliable molecular techniques essential to the diagnosis, classification, and treatment of childhood hematological disorders.

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Pediatric Hematology

Methods and Protocols

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