Oral Bioavailability - Basic Principles, Advanced Concepts and Applications

Name: Oral Bioavailability - Basic Principles, Advanced Concepts and Applications
Brand: John Wiley & Sons Inc
SKU: 9780470260999
Price: 755.31 PLN
Availability: InStock

Autor: Xiaoling Li, Ming Hu

Język:

Oprawa: Twarda

Wydawca: John Wiley & Sons Inc

Dostępność: Dostępna u dostawcy

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Understand and assess the design, delivery, and efficacy of orally administered drugs§A practical gu...

Informacje o książce

Autor

Xiaoling Li, Ming Hu

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

2011

strony

560

EAN

9780470260999

ISBN

0470260998

Enbook ID

01388197

Wydawca

John Wiley & Sons Inc

Waga

1610

Wymiary

219 x 285 x 33

Pełny opis

Understand and assess the design, delivery, and efficacy of orally administered drugs§A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability.§The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen.§This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery.§In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches-Caco-2 cell culture model, MDCK, and other related cell culture models-which are used to study the science of oral bioavailability.

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