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Książka Oncogenes Meet Metabolism G. Kroemer

Oncogenes Meet Metabolism

From Deregulated Genes to a Broader Understanding of Tumour Physiology

Autor: G. Kroemer, D. Mumberg, H. Keun, B. Riefke
Język: Angielski
Oprawa: Twarda
Wydawca: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Dostępność: Dostępna u dostawcy
Wysyłamy za 10-13 dni
649.12 zł
In 1920s, Otto Warburg described the phenomenon of aerobic glycolysis , the ability of tumour cells...

Informacje o książce

Autor
G. Kroemer, D. Mumberg, H. Keun, B. Riefke
Język
Angielski
Oprawa
Książka - Twarda
Data wydania
2008
strony
265
EAN
9783540794776
ISBN
3540794778
Enbook ID
01570245
Wydawca
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Waga
490
Wymiary
155 x 235 x 21

Pełny opis

In 1920s, Otto Warburg described the phenomenon of aerobic glycolysis , the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).

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