Książka Nuclear Factor  B R. Beyaert

Nuclear Factor B

Regulation and Role in Disease

Autor: R. Beyaert
Język: Angielski
Oprawa: Miękka
Wydawca: Springer
Dostępność: Dostępna u dostawcy w małych ilościach
Wysyłamy za 13-18 dni
470.49
The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a p...

Informacje o książce

Autor
Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2012
strony
426
EAN
9789401039833
ISBN
9401039836
Enbook ID
02184486
Wydawca
Waga
698
Wymiary
160 x 240 x 24

Pełny opis

The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. §This book is the first to review and synthesize our knowledge on this interesting transcription factor. It will be of great interest for those entering or already actively working in the NF-kappaB field, as well as a valuable reference for students, established researchers, or clinicians with wider interests in the fields of molecular cell biology and biomedicine.

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