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Molecular Insights into Proteinopathies

Name: Molecular Insights into Proteinopathies
Brand: Elsevier Science
SKU: 9780443341762
Price: 710.02 PLN
Availability: PreOrder

Increased Scope from Neurodegeneration to other Pathologies of the Brain

Autor: Eva Žerovnik, Robert Layfield

Język:

Oprawa: Miękka

Wydawca: Elsevier Science

Dostępność: Oczekiwana premiera

Wydanie 01. 10. 2026

710.02 zł

Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies...

Informacje o książce

Autor

Eva Žerovnik, Robert Layfield

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2026

strony

350

EAN

9780443341762

ISBN

0443341761

Enbook ID

50236865

Wydawca

Elsevier Science

Waga

450

Wymiary

191 x 235

Pełny opis

Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, neuropsychiatric disease. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies. The final section considers biophysical methods, molecular dynamics and machine learning approaches in the study of these aspects. This book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated. This book is an ideal reference for researchers working across cell biology, molecular biology, neuroscience and related fields.

Investigates proteostasis dysfunction across a range of proteinopathies including Alzheimer's disease and Parkinson’s disease
Considers biophysical techniques, molecular dynamics and machine learning to study molecular mechanisms
Explores small molecules as modulators of the key processes in proteinopathies
Provides a basis for further study on potential therapeutic intervention to treat proteinopathies

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Molecular Insights into Proteinopathies

Increased Scope from Neurodegeneration to other Pathologies of the Brain

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