Książka Modelling Proteasome Dynamics in a Bayesian Framework Sabine Stübler

Modelling Proteasome Dynamics in a Bayesian Framework

Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy w małych ilościach
Wysyłamy za 11-15 dni
240.86
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and a...

Informacje o książce

Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2017
strony
96
EAN
9783658201661
ISBN
3658201665
Enbook ID
18368854
Waga
1557
Wymiary
148 x 210 x 6

Pełny opis

Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S proteasome, is calibrated to experimental data from different proteasome isoforms using an approximate Bayesian computation approach. The dynamics of proteasome inhibitors are included into the model in order to demonstrate how to modulate the inhibitor's transport parameters for strong or isoform-specific inhibition.

Możesz być zainteresowany

118.77

Disreputable Persons

Blake Michael Nelson
42.54

Rebuilders

Anna Vogt
58.94
34.25

Halo's Glow

Margery Phelps
40.69
61.18

Music of Verse

Joseph Phelan
240.86
97.98

From the Bottom Up

Leigh Allison Wilson
76.99
66.06

Interrupting History

Robert John Parkes
481.73

Benjamin Franklin

Pamela McDowell
105.59

Klienci, którzy kupili tę książkę, kupili również

70.65

Le Thésée d'André Gide

Barto bianca livia
280.38

Russian Rocambole

Alexander Tsekhanovich
13.46

Einnässen im Kindes- und Jugendalter

Eberhard Kuwertz-Bröking
218.70
73.38

Le rayon vert

MR Jules Verne
64.89

Ungeschickte Briefe

Johannes Ludwig
47.81
110.86
108.13
48.69
69.87