Modeling and Optimization of Protein Expression

Name: Modeling and Optimization of Protein Expression
Brand: LAP Lambert Academic Publishing
SKU: 9783838324395
Price: 254.89 PLN
Availability: InStock

Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

Autor: Reza Gheshlaghi

Język:

Oprawa: Miękka

Wydawca: LAP Lambert Academic Publishing

Dostępność: Dostępna u dostawcy

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254.89 zł

Scientific methods of enhancing gene expression including genomics, applied molecular biology, metab...

Informacje o książce

Autor

Reza Gheshlaghi

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2009

strony

180

EAN

9783838324395

Enbook ID

06945684

Wydawca

LAP Lambert Academic Publishing

Waga

286

Wymiary

150 x 220 x 11

Pełny opis

Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentation medium components of A.niger on a recombinant protein production. Statistically based experimental designs in a sequential manner were introduced as powerful tools and applied for medium optimization. A detailed metabolic network comprising intracellular compartments, amino acid catabolism and experimental flux measurements of the key metabolites should be developed and used for optimization purposes. The proposed strategy should be useful to professionals in the field of biotechnology who seek to understand the response of microorganisms to environmental stimuli.

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Modeling and Optimization of Protein Expression

Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

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