Książka Microarray Gene Expression Data Integration and Cancer Signatures Lei Xu

Microarray Gene Expression Data Integration and Cancer Signatures

Autor: Lei Xu
Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy
Wysyłamy za 9-15 dni
212.21
Over the past decade, microarray gene expression datahas been widely used to identify cancer genesig...

Informacje o książce

Autor
Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2008
strony
120
EAN
9783639085532
ISBN
3639085531
Enbook ID
06817728
Waga
172
Wymiary
152 x 229 x 6

Pełny opis

Over the past decade, microarray gene expression datahas been widely used to identify cancer genesignatures that could complement conventionalhistopathologic evaluation to increase the accuracyof cancer diagnosis and prognosis. However, due tothe limited sample size of individual studies, thereis often only a small overlap between signatures forspecific cancers obtained in different studies. Withthe rapid accumulation of microarray data, it is ofgreat interest to understand how to combinemicroarray data across studies of similar cancers inorder to increase sample size, which could lead tothe identification of more reliable gene signaturesof specific cancers. This book provides a novelstatistical method, based on the top-scoring pairsclassifier family, for inter-study microarray dataintegration. By incorporating this new method intodifferent statistical models, we can identify robustgene signatures for cancer diagnosis and prognosisfrom integrated microarray data. This book isprimarily aimed at cancer researchers, especially inthe emerging field of cancer bioinformatics, butshould also be valuable to statisticians and medicalresearchers entering the field.

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