Książka Leucocyte Trafficking A. Hamann

Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy w małych ilościach
Wysyłamy za 13-18 dni
724.47
An essential component of inflammation is the migration of circulating leukocytes from blood into ti...

Informacje o książce

Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2013
strony
242
EAN
9783662053997
ISBN
3662053993
Enbook ID
02176289
Waga
339
Wymiary
148 x 14 x 15

Pełny opis

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.§

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