Książka Integrin-mediated Interactions between Cells and Biomimetic Materials Robert Knerr

Integrin-mediated Interactions between Cells and Biomimetic Materials

Autor: Robert Knerr
Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy
Wysyłamy za 14-21 dni
345.43
Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thes...

Informacje o książce

Autor
Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2008
strony
232
EAN
9783639042009
ISBN
363904200X
Enbook ID
06813792
Waga
345
Wymiary
152 x 229 x 12

Pełny opis

Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thesis to develop a versatile model system for an efficient and straightforward characterization of cell - biomaterial interactions on PEG-rich surfaces. The necessary compounds for this model system should allow for mimicking the surface of polymeric poly(ethyleneglycol)-rich biomaterials used for the design of cell carriers. By evaluating the adsorption of proteins and the adhesion characteristics of mammalian cells on these artificial surfaces, conclusions can be drawn, on how polymers should be engineered to achieve an optimal adhesion, growth or proliferation of cells. In particular, the consequences of an attachment of peptidic cell adhesion peptides and growth factors had to be elucidated.

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