Hypertension

Name: Hypertension
Brand: Humana Press Inc.
SKU: 9781588293237
Price: 725.1 PLN
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Methods and Protocols

Autor: Jérôme P. Fennell, Andrew H. Baker

Język:

Oprawa: Twarda

Wydawca: Humana Press Inc.

Dostępność: Dostępna u dostawcy w małych ilościach

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Our understanding of the pathogenesis of hypertension and the development of new therapies for its m...

Informacje o książce

Autor

Jérôme P. Fennell, Andrew H. Baker

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

2004

strony

502

EAN

9781588293237

ISBN

1588293238

Enbook ID

01430349

Wydawca

Humana Press Inc.

Waga

1990

Wymiary

155 x 235 x 33

Pełny opis

Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.§State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success.

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Methods and Protocols

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