Książka Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols Oliver H. Krämer

Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols

Język: Angielski
Oprawa: Miękka
Wydawca: HUMANA PR
Dostępność: Dostępna u dostawcy
Wysyłamy za 5-8 dni
748.67
This fully updated edition provides a series of methods for how best to assess functions of histone...

Informacje o książce

Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2023
strony
511
EAN
9781071627907
ISBN
1071627902
Enbook ID
44302331
Wydawca
Waga
911

Pełny opis

This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors explore the generation and evaluation of novel histone deacetylase inhibitors and new and improved techniques to assess acetylation-dependent molecular mechanisms in vitro and in vivo. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and up-to-date, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Edition serves as an ideal guide for researchers seeking to further elucidate this vital area of study.

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