Fragment Based Drug Design

Tools, Practical Approaches, and Examples

Autor: Lawrence C. Kuo

Język:

Oprawa: Twarda

Wydawca: Elsevier Science Publishing Co Inc

Dostępność: Na zamówienie

Wysyłamy za 28-34 dni

721.09 zł

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date...

Informacje o książce

Autor

Lawrence C. Kuo

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

2011

strony

645

EAN

9780123812742

ISBN

0123812747

Enbook ID

04494482

Wydawca

Elsevier Science Publishing Co Inc

Waga

1138

Wymiary

238 x 160 x 40

Pełny opis

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD

Możesz być zainteresowany

Klienci, którzy kupili tę książkę, kupili również

Najczęściej wyszukiwane

Categories

Authors

Publishers

Produkty

Produkty

Najczęściej wyszukiwane

Categories

Authors

Publishers

Produkty

Produkty

Fragment Based Drug Design

Tools, Practical Approaches, and Examples

Informacje o książce

Pełny opis

Możesz być zainteresowany

Klienci, którzy kupili tę książkę, kupili również