Feature Filtering Techniques for Biased Microarray Sample Sets

Name: Feature Filtering Techniques for Biased Microarray Sample Sets
Brand: VDM Verlag Dr. Müller
SKU: 9783639170245
Price: 205.13 PLN
Availability: InStock

Some Thoughts and Solutions

Autor: Abu Kamal

Język:

Oprawa: Miękka

Wydawca: VDM Verlag Dr. Müller

Dostępność: Na zamówienie

Wysyłamy za 17-27 dni

205.13 zł

Microarray expression data contain expression levels §of a large number of genes and have been used...

Informacje o książce

Autor

Abu Kamal

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2009

strony

EAN

9783639170245

Enbook ID

06825367

Wydawca

VDM Verlag Dr. Müller

Waga

136

Wymiary

150 x 220 x 5

Pełny opis

Microarray expression data contain expression levels §of a large number of genes and have been used in §many scientific research and clinical studies. Due §to its high dimensionalities, selecting a small §number of genes has shown to be beneficial for many §tasks such as building prediction models for a §particular disease or gene regulatory network §discovery. Traditional gene selection methods, §however, fail to take the class distribution into §the selection process. In Biomedical science, it is §very common to have microarray expression data §severely biased having very small number of diseased §samples. These biased sample sets require special §attention from researchers for identification of §genes responsible for a particular disease. In this §work, we propose three feature filtering techniques, §Higher Weight ReliefF, ReliefF with Differential §Minority Repeat and ReliefF with Balanced Minority §Repeat to identify genes responsible for fatal §diseases from biased microarray expression data. Our §solutions will help Bioinformatics, Computer Science §and Biomedical Research groups to filter potentially §hazardous genes in an efficient way.

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Feature Filtering Techniques for Biased Microarray Sample Sets

Some Thoughts and Solutions

Informacje o książce

Pełny opis

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