Książka Endotoxins: Structure, Function and Recognition Xiaoyuan Wang

Endotoxins: Structure, Function and Recognition

Język: Angielski
Oprawa: Twarda
Wydawca: Springer
Dostępność: Dostępna u dostawcy
Wysyłamy za 10-13 dni
846.32
Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathoge...

Informacje o książce

Język
Angielski
Oprawa
Książka - Twarda
Data wydania
2010
strony
415
EAN
9789048190775
ISBN
9048190770
Enbook ID
01976746
Wydawca
Waga
896
Wymiary
155 x 235 x 31

Pełny opis

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. §Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.§This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections: the first dealing with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate the Toll-like receptor TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.§The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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