Książka Ectopeptidases Jürgen Langner

Ectopeptidases

CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology

Język: Angielski
Oprawa: Twarda
Dostępność: Dostępna u dostawcy
Wysyłamy za 10-13 dni
423.79
This book has a strong focus on the role APN and DPIV play in the hematopoietic system, where again...

Informacje o książce

Język
Angielski
Oprawa
Książka - Twarda
Data wydania
2002
strony
310
EAN
9780306467882
ISBN
0306467887
Enbook ID
01379459
Waga
1420
Wymiary
155 x 235 x 23

Pełny opis

This book has a strong focus on the role APN and DPIV play in the hematopoietic system, where again signal peptides and small proteins (cytokines) are among the most interesting substrates. Additionally, both the membrane bound peptidases play roles as partners in signal transduction of lymphocytes and monocytes, and inhibition of their enzymatic activity results in cell cycle arrest, inhibition of DNA synthesis and characteristic changes of cytokine secretion pattern of T cells. This knowledge more and more is used as the base of therapeutic strategies in the treatment of a variety of inflammatory and autoimmune diseases as well as of tumors of different origin. The editors themselves with their colleagues have contributed important results about APN and DPIV that are reviewed here, and additionally, most of the leading groups in this field from Europe, U.S., Australia and Japan have contributed reviews and latest, partially unpublished results of their work.

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