Książka Chronic Lymphocytic Leukemia Ana Carolina Martinez-Torres

Chronic Lymphocytic Leukemia

From Physiology to Pathology and Therapeutic Insights

Język: Angielski
Oprawa: Miękka
Wydawca: Scholars' Press
Dostępność: Dostępna u dostawcy
Wysyłamy za 8-11 dni
221.90
Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries....

Informacje o książce

Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2014
strony
112
EAN
9783639707847
ISBN
3639707842
Enbook ID
07006383
Wydawca
Waga
177
Wymiary
152 x 229 x 7

Pełny opis

Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries. It is characterized by the accumulation of monoclonal CD5+ B-lymphocytes in blood, bone marrow, and lymphoid organs, due to an imbalance between proliferation and cell death. It is a complex disease that remains misunderstood. This book, therefore describes globally this very common but extremely complex type of leukemia. Throughout this book the principal biological hallmarks of B-cells are compared with the principal features of CLL-leukemic B-cells. Additionally the current CLL epidemiology is indicated and the most common methods of diagnosis are discussed. Moreover, the principal prognostic factors of CLL are described, passing from a medical point of view to a biological description. The major characteristics conferring apoptotic avoidance of CLL cells and proliferation factors are detailed, such as the principal models for its in vitro and in vivo study. Finally, the leading conventional treatments and new therapeutic strategies against CLL are listed with their principal biological targets.

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