Bicistronic construct:A prophylactic weapon against paratuberculosis

Name: Bicistronic construct:A prophylactic weapon against paratuberculosis
Brand: LAP Lambert Academic Publishing
SKU: 9783659924064
Price: 183.76 PLN
Availability: InStock

Autor: P. P. Goswami, S Chandrasekar

Język:

Oprawa: Miękka

Wydawca: LAP Lambert Academic Publishing

Dostępność: Dostępna u dostawcy

Wysyłamy za 5-8 dni

183.76 zł

Mycobacterium avium subsp. paratuberculosis (Map) is the causative organism of Johne's disease or pa...

Informacje o książce

Autor

P. P. Goswami, S Chandrasekar

Język

Angielski

Oprawa

Książka - Miękka

Data wydania

2016

strony

EAN

9783659924064

Enbook ID

15200278

Wydawca

LAP Lambert Academic Publishing

Waga

155

Wymiary

150 x 220 x 6

Pełny opis

Mycobacterium avium subsp. paratuberculosis (Map) is the causative organism of Johne's disease or paratuberculosis, a debilitating chronic gastroenteritis of domestic and wild ruminants. At present no effective therapeutics or vaccine candidates are available and early detection along with good management practices are the only ways to control paratuberculosis. Antigens of Map have also been used for the development of DNA vaccine. Therefore, this book, provides information about potent T cell antigen family protein of Map, PE (proline-glutamic acid rich), which has been identified, expressed in prokaryotic system. The bicistronic constructs was also generated to express two potent antigens in eukaryotic system. Further the immunogenicity was also studied alone as well as with two antigens and also immunomodulatory effect of gamma interferon in murine model. Studies revealed the importance of the bicistronic construct to develop DNA vaccine against paratuberculosis infection in animals.

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Bicistronic construct:A prophylactic weapon against paratuberculosis

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