Książka Airway Epithelium Jonathan Widdicombe

Airway Epithelium

Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy
Wysyłamy za 14-21 dni
203.29
The airways are lined with a film of fluid 10 ?m deep that acts as the first line of defense against...

Informacje o książce

Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2012
strony
148
EAN
9781615043743
ISBN
9781615043743
Enbook ID
08803889
Waga
333
Wymiary
187 x 235 x 10

Pełny opis

The airways are lined with a film of fluid 10 ?m deep that acts as the first line of defense against inhaled pathogens, dirt, and noxious vapors. Transepithelial fluid movements driven by active transepithelial ion transport serve to regulate the depth of this "airway surface liquid". In the larger airways, a mucus gel derived from both glands and surface epithelium entraps inhaled particles, which are then removed by the coordinated beating of cilia. Both glands and epithelium secrete a wide variety of antimicrobial and other protective substances in addition to mucins. Substances released across the basolateral surface of the epithelium attract leukocytes and influence neighboring tissues. Here, after reviewing the basic structure of mammalian airway epithelium, I discuss its various defensive functions and how they are altered in airway disease.

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