Advances in Osteoarthritis

Name: Advances in Osteoarthritis
Brand: Springer Verlag, Japan
SKU: 9784431702450
Price: 216.67 PLN
Availability: InStock

Autor: Chiaki Hamanishi, Seisuke Tanaka

Język:

Oprawa: Twarda

Wydawca: Springer Verlag, Japan

Dostępność: Dostępna u dostawcy

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Basic research on osteoarthritis has been carried out mainly from the his tological and biochemical...

Informacje o książce

Autor

Chiaki Hamanishi, Seisuke Tanaka

Język

Angielski

Oprawa

Książka - Twarda

Data wydania

1998

strony

298

EAN

9784431702450

ISBN

4431702458

Enbook ID

09524064

Wydawca

Springer Verlag, Japan

Waga

640

Wymiary

155 x 235 x 20

Pełny opis

Basic research on osteoarthritis has been carried out mainly from the his tological and biochemical aspects of the degenerating chondrocytes, collagen fibers, and matrix proteoglycans. Undue mechanical stress has been shown to be the principal factor in the initiation of osteoarthritis. Although the exact process by which mechanical stress leads to the total destruction of cartilage tissue remains unclear, several new research methods have enabled us to gain a deeper understanding of the process of degeneration. In October 1997, we organized an international symposium titled "Ad vances in Osteoarthritis" in Kobe, with the main topics being updated re search, diagnosis, and treatment of osteoarthritis. The proceedings of the symposium are presented here in five sections: (1) Mechanical stress and reactions of chondrocytes, such as intracellular ion changes, changes in the cytoskeleton, intracellular messenger systems, release of gas mediators, and changes in electromechanical properties of cartilage; (2) Functional diagnosis of osteoarthritis by MR imaging, and using calpain and collagenase III as new cartilage markers; (3) Treatment with a promising simple washout technique and IL-1RA and MMP antagonists; (4) Cartilage repair by new grafting tech niques; and (5) Problems following total joint replacement. We sincerely hope that the advanced knowledge provided in this volume of proceedings will be valuable to our readers.

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