Książka Actin Polymerization in Apicomplexan Avinash Kale

Actin Polymerization in Apicomplexan

Autor: Avinash Kale
Język: Angielski
Oprawa: Miękka
Dostępność: Dostępna u dostawcy
Wysyłamy za 8-11 dni
424.46
This book discusses in detail the structural, evolutionary and functional role of actin and its regu...

Informacje o książce

Autor
Język
Angielski
Oprawa
Książka - Miękka
Data wydania
2020
strony
116
EAN
9789811374524
ISBN
981137452X
Enbook ID
33446841
Waga
214
Wymiary
155 x 235 x 7

Pełny opis

This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements.The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CP and CPbeta), cyclase-associated protein (CAP) and coronin 13-24 as potential drug targets against malaria.  As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design.Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics. 

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